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Posted On: 12/06/2021 4:37:43 PM
Post# of 72446
Attached is an article I found online just now by the NIH:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC789440
2nd paragraph excerpt:
Remdesivir is highly potent with a poor solubility profile (aqueous solubility 0.339 mg/mL, 6 g of solubilizer, sulfobutylether β‐cyclodextrin sodium, SBECD for 5 mg/mL remdesivir, logP 2.0‐2.2, pKa 10.23) and is primarily renally eliminated (74%). 14 Currently approved remdesivir dosing regimen is an i.v. administered 200 mg loading dose on day 1 followed by daily maintenance dose of 100 mg as a 30‐minute infusion for up to 10 days. 15
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC789440
2nd paragraph excerpt:
Remdesivir is highly potent with a poor solubility profile (aqueous solubility 0.339 mg/mL, 6 g of solubilizer, sulfobutylether β‐cyclodextrin sodium, SBECD for 5 mg/mL remdesivir, logP 2.0‐2.2, pKa 10.23) and is primarily renally eliminated (74%). 14 Currently approved remdesivir dosing regimen is an i.v. administered 200 mg loading dose on day 1 followed by daily maintenance dose of 100 mg as a 30‐minute infusion for up to 10 days. 15
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