Hi Lvus,

Kevetrin Pharmacokinetics

Kevetrin showed a biphasic time vs. drug concentration curve with an elimination half-life of about 0.7 to 2.2 hours in mice and rats, respectively, and 1 hour in dogs and a dose dependent pattern in terms of the plasma concentration, C max, and exposure.

One half of Kevetrin is out of mice in .7 hour. I think the next .7 hour eliminates one half of the remaining 50% and then the next .7 hour eliminates one half of the remaining 25% and so on.