Posted On: 02/26/2013 11:18:12 AM
Post# of 72436
Of course human results can vary widely from animal models, and it's early in the testing, but remarks made concerning positive PK imply to me that liver enzymes are not being unduly raised (unacceptable accumulation of the drug), bioavailability (acceptable plasma concentration) is as expected, no negatives thus far.
Efficacy another matter entirely, but cant have efficacy without good PK, which is reported so far
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