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Posted On: 09/14/2021 1:46:34 PM
Post# of 153938
CDiddy,
I nearly choked on lunch reading you reply.
Most of what we take in is excreted through kidneys. Leronlimab is too large.
Eventually the target cells to which LL attaches are broken down.
The monocytes (in blood stream) take a week or so.
The macrophages (monocytes which have migrated into tissues and become more specialized) live longer, many weeks to months.
Leronlimab mostly, as best I can tell, gets broken down with those cells, with an additional fraction that failed to attach to these cells, digested just like other bits of protein floating around that seem out of place.
I nearly choked on lunch reading you reply.
Most of what we take in is excreted through kidneys. Leronlimab is too large.
Eventually the target cells to which LL attaches are broken down.
The monocytes (in blood stream) take a week or so.
The macrophages (monocytes which have migrated into tissues and become more specialized) live longer, many weeks to months.
Leronlimab mostly, as best I can tell, gets broken down with those cells, with an additional fraction that failed to attach to these cells, digested just like other bits of protein floating around that seem out of place.
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