Quote:

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Tofacitinib is a selective inhibitor of JAK1 and JAK3

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We've got that covered.

leronlimab regulates -

MapK, Erk 1 and 2, Jak 1, 2 and 3, ATP, mTORc1, TNF-a, TNFSF14, IFNy, NF-kb, bradykinin, NETosis, neuropin-1, PI3k, GM-CSF, IL1b, IL-2, IL-4, IL-6, IL-8, IL-10, IL-13, IL-17, CCL2, CCL3, CCL4, CCL5, CCL7, CCL8, CCL11, CCL13, CCL14, CCL16, VEGF, SYK, SHP1, SHP2, PD-1, C5a, CA-2+,CD38, collagen, macrophage differentiation, TGF-b