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Amyloid and tau-clearing antibodies, he wrote in a paper for the Proceeding of the National Academy of Science, might be setting off dangerous inflammation that, in a cruel bit of irony, hasten neurological decline. Lipton called the result paradoxical.

“We realized that it’s possible these human trials, many of which have failed, might be in part failing because they’re paradoxically inducing more inflammation in the brain,” he told Endpoints News, “even though they’re getting rid of the protein, which may be a good thing.”

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