That PR confirms my point.The large intestine down through the colon etc.does not "send" but only "receives" water and waste.The small intestine (through osmotic activity) distributes nutrients/meds to the bloodstream.So it's no surprise that Oral 'B' directed to the lower intestine/colon wouldn't be absorbed.The small intestinal approach has yet to be tried and I'd be surprised if it didn't work there.

Kelt