yes, that's exactly right. at my first company (investment bank), we were a small m&a boutique. the senior guys used to tell us "our product has to be twice as good as Goldman or Morgan - or we'll lose simply on the lack of name recognition." That always stuck with me.

The other quote i like is "Dance with the one who brung ya" (or something like that). We hit our primary endpoints in HIV - works like a damn charm. And if i had a friend with HIV who asked about Leronlimab, i'd go to the mat convincing him / her to use it. However, if i had a friend with COVID? Well, i'd tell them to try Leronlimab - but i would caveat that it's "better than nothing - and better than what's already out there" a much lower confidence endorsement.

I get all the stuff about low hanging fruit. but sometimes, you need to focus on what you do best - even if it means forgoing other exciting opportunities. i guess we're too far down that rabbit hole at this point however - and i really hope we get something out of COVID. we have sure as hell sunk a lot of time and resources into the chase....