"Is it reasonable to assume there is a correlation between CCR5 expression and the incidence of metastasis? In other words are cancers that dont overexpress CCR5 much less likely to metastasize?"

Follow up question, is the Angiogenesis effect on tumor growth related to CCR5 over-expression? Leronlimab halts Angiogenesis, or the blood supply that tumors trick the circulatory system to providing for a growing tumor.

Does the halting angiogenesis require the CCR5/CCL5 axis or pathway?

Metastasize or not. If you can't feed, you can't grow little Tumor. Aww, so cute, little f.cker.