Primary Endpoint of the M2M trial: change in total symptom score. Simple math as the scores are already provided by the trial site. Example: PX1 day 0 score of 8 minus day 14 score of 3, equals a 5 point reduction. A simple excel document could complete the equations..

Primary Endpoint if the S/C trial: All cause mortality at day 28. Simple math again.

There’s not much more time needed to calculate a reduction in change in symptom score then there is to calculate all cause mortality. Amarex is not hand jamming these calculations, there are programs to assist in compiling the data and making the calculations.