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Posted On: 01/11/2021 5:53:18 PM
Post# of 153886
Math with following assumptions:
1) 34.7% rate of mortality in Placebo arm
2) 90 deaths total in both cohorts (extrapolated from reported 87/394 recently)
Step 1: 0.347 X 131 = 45 patients in placebo cohort
Step 2: 90 - 45 = 45 patients in the LL cohort
Step 3: 45/263 = 17% mortality rate in the LL cohort
Step 4: 34.7-17 = 17.7 percentage points of absolute reduction
Step 5: 17.7 / 34.7 = 51% reduction in mortality
1) 34.7% rate of mortality in Placebo arm
2) 90 deaths total in both cohorts (extrapolated from reported 87/394 recently)
Step 1: 0.347 X 131 = 45 patients in placebo cohort
Step 2: 90 - 45 = 45 patients in the LL cohort
Step 3: 45/263 = 17% mortality rate in the LL cohort
Step 4: 34.7-17 = 17.7 percentage points of absolute reduction
Step 5: 17.7 / 34.7 = 51% reduction in mortality
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