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Posted On: 01/07/2021 3:41:46 PM
Post# of 153993

Re: MD VIROLOGIST #71755
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in rantes driven COVID, it is very different.
What would make a difference is the level of expression of CCR5. In that case the drug with the higher level of occupancy would have greater effect.
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If anything even in HIV Mav could be superior in binding only a head to head study would resolve that hypothesis.
With the same MOA what would be indicative of CCR5 occupancy would be the efficacy. Leronlimab has clearly superior efficacy.

