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Posted On: 12/09/2020 1:10:09 AM
Post# of 154140
Yeah, that 3 dose comment in the video didn't make sense to me at all.
From what I understand from what I've read - one 700mg dose causes almost complete occupancy of CCR5 receptors by Leronlimab, something like better than 95%. Combined with this fact, if it is indeed a fact, was the observation that Leronlimab sticks well to the CCR5 receptor for at least 60 days.
It seems to me that the second dose of 700mg in a week is plenty or perhaps even overkill. I really don't expect any unblockaded CCR5 receptors after that second dose.
This is what I believe but I'm no expert and the facts should be left to the experts like Patterson etc.
Still, if dosages, timing of doses and real knowledge of the duration of CCR5 occupancy are to be adjusted later for better effect and less waste of Leronlimab, that would be great!
Further, if my understanding is correct, I would probably prefer a dose of Leronlimab to a vaccine because I would get an immune system tune-up and the protective effects of that would probably outlast immunity I would get from a vaccine. And my immune system would be ready to take on any other infection I might get more effectively. Plus, if I already have some comorbidity going on that I didn't even know about, Leronlimab would work on that too!
Leronlimab really is a magic bullet!
From what I understand from what I've read - one 700mg dose causes almost complete occupancy of CCR5 receptors by Leronlimab, something like better than 95%. Combined with this fact, if it is indeed a fact, was the observation that Leronlimab sticks well to the CCR5 receptor for at least 60 days.
It seems to me that the second dose of 700mg in a week is plenty or perhaps even overkill. I really don't expect any unblockaded CCR5 receptors after that second dose.
This is what I believe but I'm no expert and the facts should be left to the experts like Patterson etc.
Still, if dosages, timing of doses and real knowledge of the duration of CCR5 occupancy are to be adjusted later for better effect and less waste of Leronlimab, that would be great!
Further, if my understanding is correct, I would probably prefer a dose of Leronlimab to a vaccine because I would get an immune system tune-up and the protective effects of that would probably outlast immunity I would get from a vaccine. And my immune system would be ready to take on any other infection I might get more effectively. Plus, if I already have some comorbidity going on that I didn't even know about, Leronlimab would work on that too!
Leronlimab really is a magic bullet!
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