(Total Views: 882)
Posted On: 11/13/2020 3:18:44 PM
Post# of 145248
Another view: Maraviroc, a small molecule, seats deep "in the pocket" of its binding area, deforming the CCR5 receptor and preventing its proper function. Leronlmab, a large molecule, "floats" over a broader area of the receptor, allowing its normal signaling functions to continue.
At least that argument has been on this board.
At least that argument has been on this board.
![](/m/images/thumb-up.png)
![](/m/images/thumb-down.png)