Pfizer/Biontech estimated 50 million doses worldwide shipped by the end of the year. Seeing as how Biontech is in Germany, and not to mention the cold chain shipping requirements, it will be interesting to see how and where the Pfizer/Biontech vaccine will be shipped: Europe vs. US vs. Canada vs UK vs rest of the world. I don't think the US will get a whole lot of vaccines super quick with so many also in line (and other governments already bought some?) and so many apparent logistical challenges. I think in the US, will use US military to help with those logistics, but who gets the first doses? I think maybe front line workers and elderly, or those otherwise at highest risk.

The vaccines take 3-4 weeks to generate the required immune responses, and many won't get the vaccines at all.

Overall, yes the vaccines will help (provided immunity lasts, no safety issues arise later, and no significant mutations to SARS2 / spike protein), but I don't imagine it will put a dent in US cases until the second quarter of 2021.

In the meantime, if Biden holds the presidency, expect more lockdowns and mask mandates starting in late January until we start to come out of the worst of it in late Spring 2021.

Hah, it's fun to make estimates and guesses, but nobody can predict so much of what will happen. There will be a strong need for treatments for s/c Covid for at least another 6 months I imagine. Will LL be available in 3 months?

Saw elsewhere that ivermectin looks like a good treatment, in addition to steroids. What other treatments will be available to fill the void until the vaccine gets widely distributed in the US in 6 months? Will the antiviral neutralizing antibodies be widely used for early disease? Lots of logistical challenges and costs considered for pricy IV infusion that will perhaps keep 5-10% of people at highest risk from requiring follow-up in a hospital or ED setting.