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Posted On: 10/26/2020 8:39:56 PM
Post# of 148908
Re: Borel Fields #63316
As a resident I remember we tended not to stop critical care prior to 1 month due to the desire to save life and HOPE. 40 days? No. We would consider minimal survival chances at that point.
In RLFTF the DSMC also changed the primary endpoint from 28 day mortality to “alive and free of respiratory failure at 7-10 days”. I quote, " This change in primary endpoint was driven by the general decrease in mortality with advances in treatment for Critical COVID-19 and by initial observations in the clinical trial.
Our DSMC KEPT MORTALITY AS our endpoint albeit longer duration.
In RLFTF the DSMC also changed the primary endpoint from 28 day mortality to “alive and free of respiratory failure at 7-10 days”. I quote, " This change in primary endpoint was driven by the general decrease in mortality with advances in treatment for Critical COVID-19 and by initial observations in the clinical trial.
Our DSMC KEPT MORTALITY AS our endpoint albeit longer duration.
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