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Posted On: 10/19/2020 12:48:22 PM
Post# of 149288
Calstang,
Great post and reminder of all that is known about leronlimab and why it remains such an important, albeit temporarily sidelined, therapeutic.
I believe it is pretty much settled that Leronlimab reduces formation of thrombosis. Quite a big deal IMO.
I believe that blockade of macrophage activation prevents their polarization and resultant PGEF and VGEF release, which induce thrombosis.
Ohm20 and others know the science better than I and can correct the details.
Going back to the spring, Patterson noted lack of otherwise expected thrombosis in the leronlimab treated cohort of covid patients.
Great post and reminder of all that is known about leronlimab and why it remains such an important, albeit temporarily sidelined, therapeutic.
I believe it is pretty much settled that Leronlimab reduces formation of thrombosis. Quite a big deal IMO.
I believe that blockade of macrophage activation prevents their polarization and resultant PGEF and VGEF release, which induce thrombosis.
Ohm20 and others know the science better than I and can correct the details.
Going back to the spring, Patterson noted lack of otherwise expected thrombosis in the leronlimab treated cohort of covid patients.
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