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Posted On: 10/16/2020 9:19:45 AM
Post# of 154899
Dealing with the effect of Improved mortality rates due to better ICU practices.
The negative effect that such positive ICU improvement outcomes can have on recent trials statistical significance can be reduced by cohorting trial patients based on trial dates. In trials involving a large number of patients such as the recent WHO trial of Rem, the effect of improved ICU practices can be isolated. Such figures can then be used as transformation factors to normalize smaller and recent trials based on dates such trials were performed.
The negative effect that such positive ICU improvement outcomes can have on recent trials statistical significance can be reduced by cohorting trial patients based on trial dates. In trials involving a large number of patients such as the recent WHO trial of Rem, the effect of improved ICU practices can be isolated. Such figures can then be used as transformation factors to normalize smaller and recent trials based on dates such trials were performed.
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