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Posted On: 10/16/2020 1:03:38 AM
Post# of 145254
Re: generactor #61453
Could there be a change in primary endpoint?
I agree that this is a very strong possibility #generactor.
Quote:
That would be my guess as most likely because moving the "change in clinical status" endpoint up to co-primary seems to fit as a recommendation for a potential regulatory path forward. The DMSB could have decided that the mortality endpoint was going to be too difficult to hit as mortality rates have improved with time.
I agree that this is a very strong possibility #generactor.
Quote:
That would be my guess as most likely because moving the "change in clinical status" endpoint up to co-primary seems to fit as a recommendation for a potential regulatory path forward. The DMSB could have decided that the mortality endpoint was going to be too difficult to hit as mortality rates have improved with time.
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