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Posted On: 10/09/2020 10:13:44 PM
Post# of 148941
Re: Borel Fields #60597
Borel,
Crossing the BBB as part of immune response was the first way I heard of leronlimab having an affect across the BBB. Per Scott Kelley in a CC in June/July.
The mAB actually crossing the BBB also came out of Scott Kelley‘s mouth in a recent CC, but related to Dr Sacha’s macaque studies. “70-75% receptor occupancy in brain tissue samples.”
I ‘believe’ we have confirmed in human patients that LL crosses.
But my point is, Dr Kelley said in June that we have an affect across the BBB due to immune system regulation.
Crossing the BBB as part of immune response was the first way I heard of leronlimab having an affect across the BBB. Per Scott Kelley in a CC in June/July.
The mAB actually crossing the BBB also came out of Scott Kelley‘s mouth in a recent CC, but related to Dr Sacha’s macaque studies. “70-75% receptor occupancy in brain tissue samples.”
I ‘believe’ we have confirmed in human patients that LL crosses.
But my point is, Dr Kelley said in June that we have an affect across the BBB due to immune system regulation.
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