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Posted On: 09/29/2020 9:10:20 AM
Post# of 153886
Lancet article from Friday reaffirms profound inflammation as the lethal mechanism in severe Covid.
Viral presence and immunopathology in patients with lethal COVID-19: a prospective autopsy cohort study
https://www.thelancet.com/journals/lanmic/art...0/fulltext
“ In patients with lethal COVID-19, an extensive systemic inflammatory response was present, with a continued presence of neutrophils and NETs. However, SARS-CoV-2-infected cells were only sporadically present at late stages of COVID-19. This suggests a maladaptive immune response and substantiates the evidence for immunomodulation as a target in the treatment of severe COVID-19”
Viral presence and immunopathology in patients with lethal COVID-19: a prospective autopsy cohort study
https://www.thelancet.com/journals/lanmic/art...0/fulltext
“ In patients with lethal COVID-19, an extensive systemic inflammatory response was present, with a continued presence of neutrophils and NETs. However, SARS-CoV-2-infected cells were only sporadically present at late stages of COVID-19. This suggests a maladaptive immune response and substantiates the evidence for immunomodulation as a target in the treatment of severe COVID-19”
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