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How many doses per liter after concentration and packaging? That is something I have had difficulty determining.

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CTMedic,

This information is quite dated and may not have been accurate even in its heyday. Hopefully someone with more knowledge will chime in.

However, back in May my understanding was:

- Samsung Biologics is using a 180,000 liter bioreactor for leronlimab
- The batch yield from that bioreactor is 1.2M - 350mg vials
- Each dose for COVID is 700mg (2-vials) -- administered as 2-separate 350mg abdominal shots
- Most patients have been receiving a total of 2-doses injected over two weeks (4-vials)
- There are plans for 3-doses for very Severe/Critical Patients (6-vials) – the first dose administered via IV
- There is also a possibility that Mild cases might only require 1-dose (2-vials) -- this has not been tested


Samsung produces 1.2M vials per batch
Each dose requires 2-vials
A Samsung batch represents 600k doses

- Those 600k doses can treat 300k patients (4-vials) Using current dosing standards
- Those 600k doses can treat 200k patients (6-vials) For very Severe/Critical dosing
- Those 600k doses can treat 600k patients (2-vials) Assuming possible Mild dosing


At the time, and with the help of CDiddy, I estimated Unit Pricing and calculated the impact of COGS, Royalty Payments, and Distribution Costs -- on Gross Revenue. I also calculated potential stock prices based various P/E multiples applied to Net Revenue. However, so much has changed (and become quite complicated -- see remdesivir pricing) that I don't feel it is worth including those calculations here.