On the face of it it doesn't make sense. Leronlimab blocks CCR5, HIV attaches to CCR5 but what would that have to do with any other disease. However once you know it's anti-inflammatory abilities (as a start of what it can do) then a world of possibilities opens up.

Let her know - One of the main contributing factors of Alzheimer's is the inflammatory effects of macrophages directed by cytokines to the myelin sheath which causes degradation of the sheath and damage to the synapses.

The main receptor for inflammatory cytokines is CCR5. Leronlimab blocks CCR5 drastically reducing inflammation. Leronlimab also induces macrophage differentiation lowering the number of inflammatory macrophages while simultaneously boosting CD8+ T-cells. A secondary effect is that inflammation causes a leaky blood brain barrier which allows macrophages through. With lowered inflammation the pathway for macrophage infiltration is also shut down. CCR5 also has other effects regarding memory degradation.

https://journals.sagepub.com/doi/pdf/10.1177/...7513518651

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692443/

https://ajp.amjpathol.org/article/S0002-9440(10)65542-3/pdf

https://elifesciences.org/articles/20985