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Posted On: 08/20/2020 5:32:41 PM
Post# of 145875
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I like very much this drug Aviptadil..., it is
" Vasoactive Intestinal Polypeptide " -- VIP.
It is an antiviral and immunomodulator ...
It is preventhing synthesis of cytokins and chemokines in the lungs ( including rantes ) ,
inhibits pro inflammatory TNF-alpha , IL-6 , IL-12 ,
promotes anti inflammatory IL-10...
And blocks ACE2 receptors ...
In lungs are rare cells called Alveoral type 2 cells , which are critical for a transmission of oxygen in the body , and are at very HIGH level with ACE2...
So this is why in respiratory failure ,they trying now in inhaler..
70% of VIP in our body is bound to lungs...
But we know that COVID-19 is multi-system disease.
This is why I believe that their inhaler will be great with our Leronlimab..
I will like to see study...
--1/3 patients on Aviptadil inhaler ..
--1/3 patients on Leronlimab
--1/3 patients on Aviptadil inhaler with Leronlimabb
I will not even bother with Remdesivir...
And I have this very strong feeling that Aviptadil and Leronlimab will be a BIG winner..
All IMO..
" Vasoactive Intestinal Polypeptide " -- VIP.
It is an antiviral and immunomodulator ...
It is preventhing synthesis of cytokins and chemokines in the lungs ( including rantes ) ,
inhibits pro inflammatory TNF-alpha , IL-6 , IL-12 ,
promotes anti inflammatory IL-10...
And blocks ACE2 receptors ...
In lungs are rare cells called Alveoral type 2 cells , which are critical for a transmission of oxygen in the body , and are at very HIGH level with ACE2...
So this is why in respiratory failure ,they trying now in inhaler..
70% of VIP in our body is bound to lungs...
But we know that COVID-19 is multi-system disease.
This is why I believe that their inhaler will be great with our Leronlimab..
I will like to see study...
--1/3 patients on Aviptadil inhaler ..
--1/3 patients on Leronlimab
--1/3 patients on Aviptadil inhaler with Leronlimabb
I will not even bother with Remdesivir...
And I have this very strong feeling that Aviptadil and Leronlimab will be a BIG winner..
All IMO..
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