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Posted On: 08/14/2020 9:06:27 AM
Post# of 148908
Re: stcokowner #49479
I emailed with an acquaintance who is a doctor and is up to speed on leronlimab and to a lesser degree the CytoDyn story. I asked him if he was going to put an email together to introduce health care professionals to leronlimab, what would be the most eye-catching information. Basically, what are leronlimab's "greatest hits" in the COVID space.
Here's his summary:
I thought it was pretty a pretty good recap.
Here's his summary:
Quote:
* Safe to use compared to SOC
* Most mild to moderate patients will resolve their symptoms with supportive treatment by day 14. Thus this is the most difficult group to achieve statistical significance.
* But compared to standard of care (SOC), by day 3, leronlimab showed faster clinical improvement, thus shortening hospitalization and saving the healthcare system, hospital and patients $$$. We expect that by day 14 there is no difference between leronlimab and SOC because people get better on their own in this group.
* I would also include Patterson's Montefiore data here too
a. eIND from Montefiore showed
1. normalization of CD4/CD8 ratios
2. decrease of IL-6 and RANTES by day 3
3. decrease in viral loads by day 7 and zero viral load by day 14
So to summarize:
1. Save $$$
2. Safe drug to use
3. Get people out of the hospital quicker before they progress into S/C group
4. restoration of immune system
I thought it was pretty a pretty good recap.
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