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Posted On: 08/12/2020 3:06:59 PM
Post# of 72445
besides CV19 there are these very valuable studies:
Comparative mechanistic studies of brilacidin, daptomycin, and the antimicrobial peptide LL16.
Mensa B, Howell GL, Scott R, DeGrado WF.
Antimicrob Agents Chemother. 2014 Sep;58(9):5136-45. doi: 10.1128/AAC.02955-14. Epub 2014 Jun 16.
PMID: 24936592 Free PMC article.
Brilacidin (PMX30063) has shown potent bactericidal activity against drug-resistant and -susceptible strains of multiple Gram-negative and Gram-positive pathogens. In this study, we demonstrate that brilacidin causes membrane depolarization in the Gram-positive bact …
An Independent Evaluation of a Novel Peptide Mimetic, Brilacidin (PMX30063), for Ocular Anti-infective.
Kowalski RP, Romanowski EG, Yates KA, Mah FS.
J Ocul Pharmacol Ther. 2016 Jan-Feb;32(1):23-7. doi: 10.1089/jop.2015.0098. Epub 2015 Oct 26.
PMID: 26501484 Free PMC article.
OBJECTIVE: Brilacidin (BRI), a novel defensin mimetic, was evaluated as an ocular anti-infective. METHODS: In vitro: Potency based on MIC90s was compared for 50 Staphylococcus aureus (SA), 50 Staphylococcus epidermidis (SE), and 25 each of Streptococcus pneumonia (SP), Str …
https://pubmed.ncbi.nlm.nih.gov/?term=brilacidin
Comparative mechanistic studies of brilacidin, daptomycin, and the antimicrobial peptide LL16.
Mensa B, Howell GL, Scott R, DeGrado WF.
Antimicrob Agents Chemother. 2014 Sep;58(9):5136-45. doi: 10.1128/AAC.02955-14. Epub 2014 Jun 16.
PMID: 24936592 Free PMC article.
Brilacidin (PMX30063) has shown potent bactericidal activity against drug-resistant and -susceptible strains of multiple Gram-negative and Gram-positive pathogens. In this study, we demonstrate that brilacidin causes membrane depolarization in the Gram-positive bact …
An Independent Evaluation of a Novel Peptide Mimetic, Brilacidin (PMX30063), for Ocular Anti-infective.
Kowalski RP, Romanowski EG, Yates KA, Mah FS.
J Ocul Pharmacol Ther. 2016 Jan-Feb;32(1):23-7. doi: 10.1089/jop.2015.0098. Epub 2015 Oct 26.
PMID: 26501484 Free PMC article.
OBJECTIVE: Brilacidin (BRI), a novel defensin mimetic, was evaluated as an ocular anti-infective. METHODS: In vitro: Potency based on MIC90s was compared for 50 Staphylococcus aureus (SA), 50 Staphylococcus epidermidis (SE), and 25 each of Streptococcus pneumonia (SP), Str …
https://pubmed.ncbi.nlm.nih.gov/?term=brilacidin
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