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Posted On: 07/27/2020 3:29:16 PM
Post# of 155566
From my understanding we need a test that compares two independent binomial proportions (placebo group/ leronlimab group), to compare whether the observed difference between placebo performance and leronlimab group is stat sig.
As far as I can see, your test only considers the leronlimab group in itself (like when tossing a coin 66 times and getting 60 times head, where the probability of head/tail is 50% under normal circumstances), not the difference between leronlimab and the placebo control-group (?), which is what we need, since despite the binary outcome you can't assume that the probability of dying/living is 50%.
But I'll let the guys who are actually proficient with this stuff weigh in...
As far as I can see, your test only considers the leronlimab group in itself (like when tossing a coin 66 times and getting 60 times head, where the probability of head/tail is 50% under normal circumstances), not the difference between leronlimab and the placebo control-group (?), which is what we need, since despite the binary outcome you can't assume that the probability of dying/living is 50%.
But I'll let the guys who are actually proficient with this stuff weigh in...
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