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Posted On: 07/26/2020 4:05:04 PM
Post# of 148985
Re: MD VIROLOGIST #45063
Another leronlimab path for killing the virus?
Thanks for the heads up MD VIROLOGIST. From previous reading on CCR5 I knew up about CCR5 blockade downregulating the MOTR pathway. When I saw it in the paper you posted I said Aha!
From a paper I previously read -
https://www.researchgate.net/publication/3410...y_by_HIV-1
Thanks for the heads up MD VIROLOGIST. From previous reading on CCR5 I knew up about CCR5 blockade downregulating the MOTR pathway. When I saw it in the paper you posted I said Aha!
Quote:
Inhibition of the mTOR signaling pathway using Akt inhibitor MK-2206 showed a significant reduction in virus production.
From a paper I previously read -
Quote:
CCR5 antagonists also disrupt the PI3K-AKT-mTORC1 pathway
https://www.researchgate.net/publication/3410...y_by_HIV-1
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