This confirms that currents treatments are not considered effective treatment.


In randomized clinical trials, for conditions having no effective treatment, the control regimen with which the new treatment is compared, is warranted to establish the evidence. However, when an effective treatment already exists, it is unethical to create a placebo group that will receive no treatment. In other words, patients are deprived from an already existing effective therapy. The objective of testing such drugs to establish whether the new drug is better in efficacy or safety when compared to the existing drug/s placebo controlled trial considered unethical.