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Posted On: 07/07/2020 2:19:52 AM
Post# of 145890
True, safety first. Then, how big an effect are you targeting? Remember statistical precision only grows with the square root of patients: 4x the patients ==> 2x the precision. So, all else equal, a 1600 person trial will have the same confidence in detecting, say, a 20% reduction in death rate, as a 400 person trial has in detecting a 40% drop,
My expectations for leronlimab relative risk reduction in S/C begin at 40%.
My expectations for leronlimab relative risk reduction in S/C begin at 40%.
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