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Posted On: 06/25/2020 9:12:58 AM
Post# of 148985
Quote:
GCPR is one of the most sought-after and common R&D targets
CCR5 is a GPCR, we're well ahead of the game. Most are looking at small molecule inhibitors, With CCR5 that really doesn't work out well (see maraviroc). Targeting other GPCRs is a bit of a fool's errand because it's not as effective as inhibiting CCR5.
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