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Generex Biotechnology Corp GNBT
(Total Views: 519)
Posted On: 06/08/2020 10:08:42 AM
Post# of 36567
Posted By: luisGenerex
Which is the actual phase???


Generex & Epivax have identified SARS-COV-2 amino acid peptides for epitope evaluation

2. Synthesize 2019-nCoV epitope peptides for screening (standard peptide chemistry – 11 - 15 amino acids)


3. Screen common HLA-DR alleles in vitro vs SARS-COV-2 sequences


4. Test chemical linkers with for best fit for Ii-Key (LRMK) hybrid vaccine – optimize for immunogenicity


5. Select Ii-Key Hybrid/2019-nCoV peptides for vaccine evaluation

6. Collect blood samples & isolate PBMCs from 2019-nCoV infected & recovered individuals


7. Test Ii-Key/ SARS-COV-2 hybrid peptide vaccines vs. PBMcs


8. Conduct Elispot analysis to test for IFN-γ expression indicating CD-4 T-cell activation


9. Select active Ii-Key/ SARS-COV-2 hybrid peptide vaccines for human clinical testing


10. Conduct Clinical Trial with Lead Ii-Key/SARS-COV-2 Peptides • Evaluate safety & immunogenicity (DTH Assay)


11. Select peptides for Multi-valent Ii-Key/ SARS-COV-2 Peptide Vaccine 12. Commercial Manufacturing & Distribution in 5 to 9 months













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