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Posted On: 06/07/2020 6:49:20 PM
Post# of 145902
Yep. Differences are that they are using n = 51, while I used n = 75. Also, they are using normal approximation to binomial and I am using logit. These differences will make for slight differences in the results (maybe pretty good-sized differences on very small or very large mortality rates) but nothing that matters very much...we don't know what model they'll use.
The differences that do matter are 1) 1-sample vs. 2-sample tests, which has a big influence on results (and they will definitely be using a 2-sample test), and 2) one-tail or two-tail test (and they will most likely be using a one-tail test). Also, sample size matters. Hopefully we are way above 50 by the time they cut the trial off, but we might not be.
The differences that do matter are 1) 1-sample vs. 2-sample tests, which has a big influence on results (and they will definitely be using a 2-sample test), and 2) one-tail or two-tail test (and they will most likely be using a one-tail test). Also, sample size matters. Hopefully we are way above 50 by the time they cut the trial off, but we might not be.
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