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CytoDyn Inc CYDY
(Total Views: 1213)
Posted On: 05/01/2020 5:47:42 AM
Post# of 154968
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Posted By: Rubraquercus
Re: Sunny3999 #31151
Great find! - what is RANTES ?

This list is the best summation, and I have read almost all of them.


--CytoDyn scientists believe their studies show that powerful immune modulator RANTES drives the pathogenic process of COVID-19.

--RANTES is chemoactive chemokine, expressed by many hematopoietic and non-hematopoietic cell types, that plays key role in controlling homing and migration of effector and memory T-cells during acute infections.

--RANTES receptor (CCR5) is co-receptor for HIV and a major target of anti-HIV drugs based on blocking viral entry.

--RANTES levels are highly elevated in COVID-19 patients and RANTES fundamentally drives the COVID-19 pathogenic process via binding of RANTES to CCR5.

--CytoDyn’s drug, a humanized monoclonal antibody called leronlimab, blocks CCR5, denying binding access to RANTES.

--Levels of RANTES return to normal very quickly after single sub-cutaneous injection of leronlimab

--Disease-associated high levels of interleukin-6, and of other chemokines, are quickly reduced to normal.

--Lung function is restored.

--Plasma viral load is reduced.

--Drug delivered by one subcutaneous injection.

http://www.bioquicknews.com/node/5307


























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