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Posted On: 04/16/2020 1:25:46 AM
Post# of 72440
It is hard to say. It has been used in compassionate use for advanced COVID19 and an Ebola trial. It is hard to pick out the side effects of the drug versus the gruesome diseases. Hepatic toxicity concerns have been mentioned..There were some healthy human volunteers included in the Ebola study. No results were posted including AE or SAE on clinicaltrials.govBelow is a blip which mentions the Phase 1 study where Remdesivir" doses" were safely administered"
"Clinical safety profile from > 100 human subjects dosed with intravenous remdesivir supports the clinical dosing regimen recommended for the treatment of Ebola. Single and repeated doses of remdesivir were safely administered in Phase 1 studies in healthy human subjects, PREVAIL IVstudy in male Ebola virus disease (EVD) survivors, as well as during compassionateuse for the treatment and post exposure prophylaxis ofEbola infection.
That is all I could dig out. I will try to take another look for it later.
Good luck,Farrell
"Clinical safety profile from > 100 human subjects dosed with intravenous remdesivir supports the clinical dosing regimen recommended for the treatment of Ebola. Single and repeated doses of remdesivir were safely administered in Phase 1 studies in healthy human subjects, PREVAIL IVstudy in male Ebola virus disease (EVD) survivors, as well as during compassionateuse for the treatment and post exposure prophylaxis ofEbola infection.
That is all I could dig out. I will try to take another look for it later.
Good luck,Farrell
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