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Posted On: 01/22/2020 8:27:54 AM
Post# of 149265
Downregulates programmed death ligand 1 (PD-L1 helps protect against attacks by T-cells). Downregulates angiogenesis (growth of blood vessels) throughout the tumor by limiting chemokine signalling which helps kill off the tumor. Reduces collagen deposition, fibronectin, and tenascin C which tumors use to grow and survive. Suppresses expression of immunosuppressive myeloid cells, immunosuppressive myeloid cells keep T-cells from attacking tumors. Shuts down tyrosine kinase receptors which reduces tumor cell proliferation. Downregulation of interleukin 6, which reduces tumor growth.
There are probably others.
There are probably others.
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