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Posted On: 01/18/2020 4:01:06 PM
Post# of 153964
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I do know that CTC is though.
NK is not using CTC as an endpoint, however Tyme has measured CTCs and shown their importance.
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Additional analyses were conducted to show the association between CTCs and survival. The median decrease of CTCs was 63%, and 56.3% of patients with CTC decreases had an OS of >180 days compared with 37.5% of those with CTC increases. Patients who had ≥80% CTC reduction (n = 24) trended toward improved OS (HR, 0.4; 95% CI, 0.11-1.5; P = 1., and those with ≤50 cells/4 mL at nadir also had favorable OS outcomes (HR, 0.64; 95% CI, 0.2-2.1; P = .45). Patients with the longest survival at 261+, 262+, and 343+ days had both an >80% reduction and <50 cells/4 mL.
https://www.targetedonc.com/news/study-of-sm8...tic-cancer
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