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Posted On: 01/12/2020 4:20:07 AM
Post# of 153864
Re: tconway1118 #14822
Quote:
[to just propose that leronlimab will mitigate this without proper pre-clinical studies, etc., is irresponsible.
Where have I proposed no clinical trials. Of course there would be trials, how else do you get FDA approval, Do you think I'm going to get a hold of some leronlimab and start injecting my friends who might have the flu? Research on a drug first takes someone making a proposal, I just did in this thread.
Quote:
[This study is particularly on point as to the complicated relationship between CCR5 and inflammation. In this case, specifically with influenza A:
That study is based on CCR5 delete mice. That's not even similar to CCR5 delta 32 because no work-around to the immune system has taken place. With CCR5 delete mice you have a very low immune response right out of the box.
My suggestion was potential with leronlimab when there was an overactive immune response. Definitely apples and oranges.
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