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Posted On: 12/15/2019 2:53:19 PM
Post# of 85938
Good Afternoon Univec Conglomerate Investors. I often post about the importance of high-grade processing and the state of the art in the cannabis industry, but there is one thing that fascinates me most, and it is the subject of CBD and nanotechnology.
The main reason being that I’ve learned so much more about the biological and chemical challenges of optimizing the bioavailability of cannabidiol (CBD). In other words, I’ve realized that the story isn’t about the efficacy and well-documented Cannabis science, it’s all about what CBD nanotechnology is bringing to Federal agencies and State and Local Taxing Authorities.
Trillions have been invested by big pharma in nano-science over the last three decades, but curiously little has been invested in delivery systems for drug medications --- until now. Hence, the interest in a CBD transdermal patch.
What is nanotechnology? Nanotechnology achieves the objective of manipulating atoms, molecules, and supramolecular formations and reducing their scale to between 1 and 100 nanometers (nm) according to the National Nanotechnology Initiative.
You can say that this means that our scientists are reducing particles and materials to one-millionth of their original size and even further.
Current examples of nanotechnology are now widespread including nano-medicine, biomaterials, microscopic devices, robots, computer chips, and essential organic compounds like CBD.
It wasn’t until the 80’s and the invention of scanning tunneling microscopes that we were able to actually see the nano-particles we were forming!
Today, scientists, physicians, and engineers are becoming very familiar with reducing the size of atoms, molecules… and yes, even physical devices to nanoscale. This is how they are realizing the enhanced properties of these particles and devices to achieve 100% bioavailability of organic phytonutrients like CBD compared to their original size counterparts.
No doubt about it. The primary trend in CBD manufacturing is nano-enhanced (nano-sized) cannabidiol (CBD). If you are a user of CBD hemp oil, you are probably well aware of this due to the number of new products increasing each month that “claim” to be incorporating nano-technology into their products and manufacturing.
The attractiveness and possibilities of nanotechnology and CBD began to take off after 2010. The reason for this is as follows:
• Creation of a 100% bioavailable delivery system for optimum effect
• Effective distribution throughout the body per dose
• Speed of delivery is significantly increased
* Better economies of scale in manufacturing – profit potential
Never before has nano-sized cannabidiol clusters been so stable in solution (water for example). And it is this development that has attracted the attention of the Federal Drug Administration (FDA) currently evaluating the efficacy of CBD nano-emulsification patented technologies.
In short, CBD nano-emulsified products will likely be the first FDA approved CBD products. And if that doesn’t excite you, then absolutely nothing will.
Creating pharmaceutical quality CBD products is about as high a bar a cannabis company can set for itself. And this is the clear objective with respect to a number of patents pending current review by the FDA. CBD companies and lab facilities are also applying for FDA Authorized Lab approvals and licenses which would be a CBD industry first.
Consumers expect product homogeneity, high quality, safety, and nano CBD products must be stabilized and duplicable. Otherwise, these products will not the meet strict homogeneity criteria required by the FDA and consumers alike.
Strict manufacturing standards and guidance for the human pharmaceutical industry is provided by the “Current Good Manufacturing Practice” regulations (CGMP). Further guidance for the industry includes “Packaging, Labeling, or Holding Operations for Dietary Supplements.”
Few people are aware of CGMPs, and how the FDA’s mandate to assure drug manufacturing standards, practices, and processes are changing the industry.
A word of caution. What I can discern from my own research is that the term “nano-enhanced hemp oil” can only be taken at face value. I find it difficult to find substantial proof online from most manufacturers. And from what I read in the highest ranked blog posts on the subject, I am amazed at the in-your-face inaccuracies and misinformation contained in them. I’ve found that most manufacturers are simply replicating well-established lyposomal, colloidal and/or micelle technologies and using standardized equipment. Nothing really new, and of course every company will argue that “theirs” is better than another due to their chemical and procedural approaches.
The problem with nano CBD product manufacturing is that CBD is very difficult to work with. Quite different than adding CBD isolate to oil, and then placing an attractive label on it. Many of product websites make the most ignorant statements and claims from a biochemistry standpoint and thereby reveal their shortcomings and lack of scientific value. Thus, buyer beware.
Simply put, not all nano CBD products are created equal.
REFERENCES:
https://www.ncbi.nlm.nih.gov/pubmed/16304818
https://www.nano.gov/nanotech-101/what/definition
https://www.fda.gov/Drugs/DevelopmentApproval...169105.htm
http://blog.sonomechanics.com/blog/ultrasonic...nnabinoids
https://www.prnewswire.com/news-releases/cbd-...21169.html
http://eng.thesaurus.rusnano.com/wiki/article1199
https://www.genome.gov/27532724/epigenomics-fact-sheet/
https://becomingasuperhuman.com/nootropics-bi...en-fowkes/
Kgem
The main reason being that I’ve learned so much more about the biological and chemical challenges of optimizing the bioavailability of cannabidiol (CBD). In other words, I’ve realized that the story isn’t about the efficacy and well-documented Cannabis science, it’s all about what CBD nanotechnology is bringing to Federal agencies and State and Local Taxing Authorities.
Trillions have been invested by big pharma in nano-science over the last three decades, but curiously little has been invested in delivery systems for drug medications --- until now. Hence, the interest in a CBD transdermal patch.
What is nanotechnology? Nanotechnology achieves the objective of manipulating atoms, molecules, and supramolecular formations and reducing their scale to between 1 and 100 nanometers (nm) according to the National Nanotechnology Initiative.
You can say that this means that our scientists are reducing particles and materials to one-millionth of their original size and even further.
Current examples of nanotechnology are now widespread including nano-medicine, biomaterials, microscopic devices, robots, computer chips, and essential organic compounds like CBD.
It wasn’t until the 80’s and the invention of scanning tunneling microscopes that we were able to actually see the nano-particles we were forming!
Today, scientists, physicians, and engineers are becoming very familiar with reducing the size of atoms, molecules… and yes, even physical devices to nanoscale. This is how they are realizing the enhanced properties of these particles and devices to achieve 100% bioavailability of organic phytonutrients like CBD compared to their original size counterparts.
No doubt about it. The primary trend in CBD manufacturing is nano-enhanced (nano-sized) cannabidiol (CBD). If you are a user of CBD hemp oil, you are probably well aware of this due to the number of new products increasing each month that “claim” to be incorporating nano-technology into their products and manufacturing.
The attractiveness and possibilities of nanotechnology and CBD began to take off after 2010. The reason for this is as follows:
• Creation of a 100% bioavailable delivery system for optimum effect
• Effective distribution throughout the body per dose
• Speed of delivery is significantly increased
* Better economies of scale in manufacturing – profit potential
Never before has nano-sized cannabidiol clusters been so stable in solution (water for example). And it is this development that has attracted the attention of the Federal Drug Administration (FDA) currently evaluating the efficacy of CBD nano-emulsification patented technologies.
In short, CBD nano-emulsified products will likely be the first FDA approved CBD products. And if that doesn’t excite you, then absolutely nothing will.
Creating pharmaceutical quality CBD products is about as high a bar a cannabis company can set for itself. And this is the clear objective with respect to a number of patents pending current review by the FDA. CBD companies and lab facilities are also applying for FDA Authorized Lab approvals and licenses which would be a CBD industry first.
Consumers expect product homogeneity, high quality, safety, and nano CBD products must be stabilized and duplicable. Otherwise, these products will not the meet strict homogeneity criteria required by the FDA and consumers alike.
Strict manufacturing standards and guidance for the human pharmaceutical industry is provided by the “Current Good Manufacturing Practice” regulations (CGMP). Further guidance for the industry includes “Packaging, Labeling, or Holding Operations for Dietary Supplements.”
Few people are aware of CGMPs, and how the FDA’s mandate to assure drug manufacturing standards, practices, and processes are changing the industry.
A word of caution. What I can discern from my own research is that the term “nano-enhanced hemp oil” can only be taken at face value. I find it difficult to find substantial proof online from most manufacturers. And from what I read in the highest ranked blog posts on the subject, I am amazed at the in-your-face inaccuracies and misinformation contained in them. I’ve found that most manufacturers are simply replicating well-established lyposomal, colloidal and/or micelle technologies and using standardized equipment. Nothing really new, and of course every company will argue that “theirs” is better than another due to their chemical and procedural approaches.
The problem with nano CBD product manufacturing is that CBD is very difficult to work with. Quite different than adding CBD isolate to oil, and then placing an attractive label on it. Many of product websites make the most ignorant statements and claims from a biochemistry standpoint and thereby reveal their shortcomings and lack of scientific value. Thus, buyer beware.
Simply put, not all nano CBD products are created equal.
REFERENCES:
https://www.ncbi.nlm.nih.gov/pubmed/16304818
https://www.nano.gov/nanotech-101/what/definition
https://www.fda.gov/Drugs/DevelopmentApproval...169105.htm
http://blog.sonomechanics.com/blog/ultrasonic...nnabinoids
https://www.prnewswire.com/news-releases/cbd-...21169.html
http://eng.thesaurus.rusnano.com/wiki/article1199
https://www.genome.gov/27532724/epigenomics-fact-sheet/
https://becomingasuperhuman.com/nootropics-bi...en-fowkes/
Kgem
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