(Total Views: 449)
Posted On: 12/11/2019 2:23:59 PM
Post# of 153903
Re: craigakess #12486
Yes CAR-T treatment sound very good here , but it is a very dangerous treatment , this is why it is offer only to people without other options...
Usually done in ICU in the hospital , still about 15% mortality due to treatment ...
WE see...
--multi organ failure,
--severe drop of BP,
--neurotoxicity,
--violent seizures ,
It is believe that many of those side effects are because of........
" Cytokine Release Syndrome "
We can see this in about 50% of the patients...it is damage to immune cells.
First T-cells are activated ,they recruiting cytokines, cytokines than recruit more immune cells...
During our last CC ( I think last one ) someone was asking about CAR-T treatment , and DR Patterson came to talk , and in his opinion Leronlimab may help here too..
All IMO...
Usually done in ICU in the hospital , still about 15% mortality due to treatment ...
WE see...
--multi organ failure,
--severe drop of BP,
--neurotoxicity,
--violent seizures ,
It is believe that many of those side effects are because of........
" Cytokine Release Syndrome "
We can see this in about 50% of the patients...it is damage to immune cells.
First T-cells are activated ,they recruiting cytokines, cytokines than recruit more immune cells...
During our last CC ( I think last one ) someone was asking about CAR-T treatment , and DR Patterson came to talk , and in his opinion Leronlimab may help here too..
All IMO...
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