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Posted On: 12/10/2019 8:42:08 AM
Post# of 154029
Re: LaundryMoney #12356
One of the reasons for my posts searching around for brain/ccr5
https://investorshangout.com/post/view?id=5611149
was after NP saying his mother-in-law metastasis was also in the brain and wondering if leronlimab can help with that because the blood brain barrier is harder for large molecules.
I know that Biogen showed in a recent finding that aducanumab crossed the blood brain barrier at high doses.
https://www.statnews.com/2019/10/23/aducanuma...ers-drugs/
Also some old research in using other drugs to get mabs across the bbb.
https://www.sciencedaily.com/releases/2010/05...175257.htm
https://investorshangout.com/post/view?id=5611149
was after NP saying his mother-in-law metastasis was also in the brain and wondering if leronlimab can help with that because the blood brain barrier is harder for large molecules.
I know that Biogen showed in a recent finding that aducanumab crossed the blood brain barrier at high doses.
https://www.statnews.com/2019/10/23/aducanuma...ers-drugs/
Quote:
What emerged from the updated analyses is that the dose of aducanumab that gets across the blood-brain barrier and the duration of treatment matter.
Also some old research in using other drugs to get mabs across the bbb.
https://www.sciencedaily.com/releases/2010/05...175257.htm
Quote:
New research suggests that a drug currently approved to treat erectile dysfunction may significantly enhance the delivery of the anti-cancer drug herceptin(Trastuzumab) to certain hard-to-treat brain tumors. The research could help doctors improve treatments for lung and breast cancers that have metastasized to the brain.
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