(Total Views: 126)
Posted On: 10/09/2019 1:19:15 PM
Post# of 44029
$GTBP alert ~ Huge news last week updating HIV TriKE™ >>
GT Biopharma Announces HIV TriKE™ Data Demonstrating NK Cell Killing of Patient HIV Infected Cells
https://finance.yahoo.com/news/gt-biopharma-a...00239.html
To Note: "Research findings from Dr. Schacker's and Dr. Miller's laboratories show enhanced NK cell cytokine production and killing of infected targets expressing HIV-Env when incubated with the HIV-TriKE™. Peripheral blood mononuclear cells (T-cells, B-cells, NK cells and monocytes) from healthy donors incubated with the HIV-TriKE™ showed marked increases in immune cell activation in NK cell, CD4 T-cell and CD8 T-cell population subsets. The HIV-TriKE™ also induced NK cell proliferation, and demonstrated the ability in vitro to reactivate and kill HIV-infected T-cells.
These findings indicate a potential role for the HIV-TriKE™ in the reactivation and elimination of the latently infected HIV reservoir cells by harnessing the NK cell's ability to mediate the antibody-directed cellular cytotoxicity (ADCC)."
GT Biopharma Announces HIV TriKE™ Data Demonstrating NK Cell Killing of Patient HIV Infected Cells
https://finance.yahoo.com/news/gt-biopharma-a...00239.html
To Note: "Research findings from Dr. Schacker's and Dr. Miller's laboratories show enhanced NK cell cytokine production and killing of infected targets expressing HIV-Env when incubated with the HIV-TriKE™. Peripheral blood mononuclear cells (T-cells, B-cells, NK cells and monocytes) from healthy donors incubated with the HIV-TriKE™ showed marked increases in immune cell activation in NK cell, CD4 T-cell and CD8 T-cell population subsets. The HIV-TriKE™ also induced NK cell proliferation, and demonstrated the ability in vitro to reactivate and kill HIV-infected T-cells.
These findings indicate a potential role for the HIV-TriKE™ in the reactivation and elimination of the latently infected HIV reservoir cells by harnessing the NK cell's ability to mediate the antibody-directed cellular cytotoxicity (ADCC)."
(0)
(0)
