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Posted On: 08/10/2019 8:00:50 PM
Post# of 149275
Yes, I knew we would miss one or two, those macrophage contributing collagen are also related to recurrence, promotes mestastasis, a lot of connections.
COLLAGEN-MUNCHING ENZYME HELPS TUMORS SPREAD
The enzyme enables tumor cells to tunnel through collagen, creating a convenient path for tumors to spread cancer throughout the body
CCL5 promotes tumor recurrence by recruiting CCR5-expressing macrophages, which may contribute to collagen deposition in residual tumors. Blocking this TNFα-CCL5-macrophage axis may be efficacious in preventing breast cancer recurrence
COLLAGEN-MUNCHING ENZYME HELPS TUMORS SPREAD
The enzyme enables tumor cells to tunnel through collagen, creating a convenient path for tumors to spread cancer throughout the body
CCL5 promotes tumor recurrence by recruiting CCR5-expressing macrophages, which may contribute to collagen deposition in residual tumors. Blocking this TNFα-CCL5-macrophage axis may be efficacious in preventing breast cancer recurrence
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