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Posted On: 06/13/2019 6:28:24 AM
Post# of 155253
The list with research linking CCR5 expression to (poor prognosis of) cancers is getting longer and longer
Prognostic value of immunoexpression of CCR4, CCR5, CCR7 and CXCR4 in squamous cell carcinoma of tongue and floor of the mouth
“Conclusions
Finally, our results show that CCR7 and CCR5 can be helpful as prognostic markers and as a therapeutic ap- proach of patients with SCC of tongue and floor of the mouth. The association of CCR5 and CCR7 chemokine/ chemokine receptor axis with poor prognosis in oral SCC needs future molecular research to study mecha- nisms that lead to tumor growth and progression, con- sidering that immunohistochemical studies can only confirm statistical relationship.”
http://www.medicinaoral.com/pubmed/medoralv24_i3_p354.pdf
Prognostic value of immunoexpression of CCR4, CCR5, CCR7 and CXCR4 in squamous cell carcinoma of tongue and floor of the mouth
“Conclusions
Finally, our results show that CCR7 and CCR5 can be helpful as prognostic markers and as a therapeutic ap- proach of patients with SCC of tongue and floor of the mouth. The association of CCR5 and CCR7 chemokine/ chemokine receptor axis with poor prognosis in oral SCC needs future molecular research to study mecha- nisms that lead to tumor growth and progression, con- sidering that immunohistochemical studies can only confirm statistical relationship.”
http://www.medicinaoral.com/pubmed/medoralv24_i3_p354.pdf
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