The attached link is a reasonable overview of the varied functions of beta defensins in human physiology. It is a field of intense interest for some researchers. Despite what some will say, the science is solid. IPIX is attempting to introduce a completely novel class to market and the bar will be higher for them. Keep this in mind when you read some of the uninformed rhetoric. Having worked both clinically and on bench research in the field, The current therapies, in my estimation, are lacking due to them BLOCKING certain compounds (eg TNF Alpha) as opposed to the addition of a compound which may be in relative scarcity, which is more preferable from a side effect perspective. Blocking intrinsic molecules effectively accepts that you are blocking their multiple functions which lead to morbidity.

But never forget that the industry scientists who are reviewing Brilacidin know its potential. Not all defensin classes have the same functions and it remains to be seen B’s potential.

https://www.researchgate.net/profile/Giovanna...ion_detail