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Posted On: 04/09/2019 1:47:09 PM
Post# of 149693
FDA approves.... "Dovato" .....Dolutegravil /Lamivudine for treatment -naive patients ....
" 2 drugs regimen in a single tabl ,while eliminating additional toxicity and potential drug interactions from a third drug "
and for patients with no resistance to this drugs ,....
-2% of patients withdrew from study because of serious side effects ,
- severe hypersensitivity may happen ,
including organ dysfunction and liver injury have been reported with Dolutegravil .
Discontinue DOVATO immediately if any sign or symptoms .
-Lactic acidosis and severe hepatomegaly with steatosis , including fatal cases have been reported with nucleoside analogues ..
-contraindicated with patient with kidney or liver impairment ..
- drug interaction may happen , check with your physician..
-Human Reconstitution Syndrome , has been reported ( autoimmune reaction )
-and in addition to other less severe side effects , patients may develop resistant Hepatitis B , so...
-The labeling includes a Boxed Warning that patients with Hepatitis B may develop resistant Hepatitis B and liver toxicities , including liver failure ..
" 2 drugs regimen in a single tabl ,while eliminating additional toxicity and potential drug interactions from a third drug "
and for patients with no resistance to this drugs ,....
-2% of patients withdrew from study because of serious side effects ,
- severe hypersensitivity may happen ,
including organ dysfunction and liver injury have been reported with Dolutegravil .
Discontinue DOVATO immediately if any sign or symptoms .
-Lactic acidosis and severe hepatomegaly with steatosis , including fatal cases have been reported with nucleoside analogues ..
-contraindicated with patient with kidney or liver impairment ..
- drug interaction may happen , check with your physician..
-Human Reconstitution Syndrome , has been reported ( autoimmune reaction )
-and in addition to other less severe side effects , patients may develop resistant Hepatitis B , so...
-The labeling includes a Boxed Warning that patients with Hepatitis B may develop resistant Hepatitis B and liver toxicities , including liver failure ..
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