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Posted On: 03/27/2019 9:14:30 PM
Post# of 150132
Looks like they will be running tests on failures vs responders. Sounds like a dna test, using terms like heterozygous, to predict ccr5 density and expression instead of a direct measure. Anyway, 6-8 weeks wait for results to submit the mono pivotal, sounds to me like they will include this in the protocol assuming the tests shows a strong correlation, which I am assume it will. Basically I feel very strongly the ccr5 density vs dose vs failure would show, just unknown if ccr5 density can be predicted with a dna test. When I get time I will do a little research seeing if certain rs# map this,
https://www.snpedia.com/index.php/CCR5
https://www.snpedia.com/index.php/CCR5
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