So let me explain how pharma works for you, let's pick an applicational area, specifically diabetes, our partnering universe is 4 companies on this whole planet, lilly (which Gnbt blew) sanofi, novo and one other small that's it, everyone thinks there are 1000 pharmaceutical companies out there I should partner, well it don't work that way not all are in diabetes and not all sell insulin in one form or another, so blown asset, 4 potential partners including one you've already pissed off, this is just common sense stuff.