RP and the PI in the TNBC trial who is the CTC expert, Dr. Massimo Cristofanill, go back quiet a ways. They created a plan which has taken years to reach this point, the first TNBC trial with the Ccr5 inhibitor Leronlimab using CTC numbers as a gauge for progress.

http://blogs.jefferson.edu/atjeff/2013/02/12/...anilli-md/

And patent application together in 2016

https://patents.google.com/patent/WO2016209926A1/en