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Posted On: 02/04/2019 4:39:52 PM
Post# of 154852
Thanks fine, here is another quote from your blog on the same vain. For the 700mg flu failure, I will have to search again to see what NP said, it was during a CC.
I remember in the same CC following that statement, NP saying people would be just fine on 350mg, which seems to me to ignore that IC90 concept.
I remember in the same CC following that statement, NP saying people would be just fine on 350mg, which seems to me to ignore that IC90 concept.
Quote:
It might help to have the patient’s CCR5 density measured if possible and PRO 140’s concentration in blood over time. Most importantly the CCR5 Occupancy over time shall be measured, aggregating aforementioned CCR5 density and PRO 140 concentration. In case this data exposes a correlation with the viral rebound group, support for the high dosage arm would be well founded. Cause of lower CCR5 Occupancy could be higher individual CCR5 density and lower PRO 140 levels
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